The leading experts from the University of Bristol’s School of Cellular and Molecular Medicine are at the heart of much of the UNCOVER research activity. In this series of short films, a few of the UNCOVER scientists discuss how they are address the challenges posed by the COVID-19 pandemic.
COVID-19 research: Improving drug delivery (Dr Allison Blair)
Dr Allison Blair, Associate Professor in Experimental Haematology in the University of Bristol’s School of Cellular and Molecular Medicine discusses her team’s work to adapt cancer drug delivery systems to help fight COVID-19.
Prof Ruth Massey, Professor of Microbial Pathogenicity in the University of Bristol’s School of Cellular and Molecular Medicine, discusses her team’s work to improve tests for dangerous secondary infections in COVID-19 patients.
COVID-19 research: Understanding the immune response (Prof Fernando Ponce)
Prof Fernando Ponce, PhD candidate in the University of Bristol’s School of Cellular and Molecular Medicine, discusses his work to understand the role of neutrophils (a key form of white blood cell and the first line of defence against infection) in the body’s immune response to SARS-CoV2.
Jonathan Reid, Professor of Physical Chemistry, talks to Professor John Iredale, Pro Vice-Chancellor for Health and Life Sciences, about his team’s work to understand the mechanisms that enable a virus like COVID-19 to spread.
Dr Ellen Brooks Pollock, Senior Lecturer in Infectious Disease Mathematical Modelling, talks to Professor John Iredale, Pro Vice-Chancellor for Health and Life Sciences, about infectious disease modelling and how this work is underpinning the COVID-19 public health response of governments around the world.
A new COVID-19 Protein Portal providing UK scientists with free access to protein reagents for critical SARS-CoV-2 research launched on 12th May. The Portal, in response to a Wellcome and UKRI Open Science initiative, is led by a consortium of leading protein production laboratories including the MultiBac expression facility in the University of Bristol’s School of Biochemistry.
Healthy frontline NHS staff in Bristol will be studied as part of a ground-breaking research project led by infectious disease and immunology specialists from Bristol Royal Hospital for Children and the University of Bristol. Researchers will track their symptoms (or lack of), the presence (or absence) of the virus in their mouths and noses and the development (or not) of the protective antibodies in their blood over a three-month period.
In December 2019, there was just one lab in the country researching coronavirus, which was here in Bristol. Researchers from Bristol’s School of Cellular and Molecular Medicine (CMM) have been growing the live human SARS-CoV-2 virus in a controlled lab to investigate what the virus is doing inside monkey and human cells. Doctors David Matthews and Andrew Davidson from the CMM have already published the first UK paper describing the important genetic changes that occur when SARS-COV-2 spreads in the body.