Andrew Davidson, Darryl Hill and David Matthews et al.
The work: Cell biology and virology of Live SARS-CoV-2, including; viral genetics, mutations, neutralization, diagnostics, detection, and infection pathogenesis, as well as the calibration of antibodies, drugs, and the generation of lower pathogenicity viruses for drug testing. All work is carried out in a high level containment lab. In December 2019, this lab was the only one in the UK researching coronaviruses.
Links: Public Health England
Funding: EBI Rapid Response, DARO funding for essential equipment, BBSRC, MRC
In news and features:
Characterisation of the transcriptome and proteome of SARS-CoV-2 using direct RNA sequencing and tandem mass spectrometry reveals evidence for a cell passage induced in-frame deletion in the spike glycoprotein that removes the furin-like cleavage site